Xiaflex (collagenase clostridium histolyticum) (Auxilium Pharmaceuticals Inc.) for Dupuytren contracture

Hayes, Inc.
Record ID 32011000856
English
Authors' objectives:

Dupuytren contracture affects the fascia (connective tissue) in the palm of the hand, which covers the tendons responsible for flexing the fingers. This disease causes toughening and contraction of the fascia. Over time, the formation of tissue knots and thick cords under the skin pulls the affected finger or fingers into a permanently bent position. Although the cause of Dupuytren contracture is unknown, it is more common in men and in patients who have diabetes, seizure disorders, and epilepsy. The most common treatment for this disorder is fasciectomy, surgical removal of the diseased fascia through open incisions in the hand and fingers.

Details
Project Status: Completed
Year Published: 2010
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
MeSH Terms
  • Clostridium histolyticum
  • Microbial Collagenase
  • Dupuytren Contracture
Contact
Organisation Name: HAYES, Inc.
Contact Address: 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name: saleinfo@hayesinc.com
Contact Email: saleinfo@hayesinc.com
Copyright: <p>HAYES, Inc.</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.