Postpartum hemorrhage, which occurs after the placenta is delivered, is the leading cause of pregnancy-related deaths worldwide, with an estimated 140,000 deaths occurring each year. The annual incidence of postpartum hemorrhage has been reported to range from 4% to 6%. The most common cause of primary postpartum hemorrhage is uterine atony, which is the failure of the uterus to sufficiently contract after delivery, followed by genital tract trauma. First-line therapy to stop postpartum bleeding includes pharmaceutical management with uterotonics, such as oxytocin, methylergometrine, and prostaglandins. Women whose bleeding fails to respond to first-line medical interventions are subsequently treated with second-line treatments, including bimanual uterine compression or gauze packing. Uterine balloon tamponade procedures have been investigated as an adjunctive, conservative treatment to arrest postpartum bleeding before proceeding to invasive surgeries that carry greater risk of morbidity and potential loss of fertility.