Inert liquid-to-solid gels for prostate-rectum separation during prostate radiation therapy

Australian Safety and Efficacy Register of New Interventional Procedures - Surgical (ASERNIP-S)
Record ID 32011000728
English
Authors' recommendations: From the limited literature available (four small studies limited in rigour of design), some form of injected liquid-to-solid inert substance (mostly recently cross-linked hyaluronan gel) for prostate-rectum separation appears to be safe. It also appears to have the potential to lower rates of rectal toxicity and improve QOL for men receiving radiotherapy for prostate cancer. However, the technology is very early in its lifecycle and is not yet in clinical use, although a recent press release notes clinical application of SpaceOAR in Germany. Cost data were not available. Although the treatment paradigm is appealing, more research is definitely needed before conclusions can be reached as to the technology’s potential place in therapy.
Details
Project Status: Completed
URL for project: http://www.horizonscanning.gov.au/internet/horizon/publishing.nsf/Content/8DA46B03741CB76FCA2577570016E96C/$File/PS%20Inert%20gels%20for%20prostate-rectum%20separation.pdf
Year Published: 2010
URL for published report: http://www.horizonscanning.gov.au/internet/horizon/publishing.nsf/Content/8DA46B03741CB76FCA2577570016E96C/$File/PS%20Inert%20gels%20for%20prostate-rectum%20separation.pdf
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Australia
MeSH Terms
  • Prostatic Neoplasms
  • Hydrogels
  • Radiation Injuries
  • Rectum
  • Radiotherapy Dosage
Contact
Organisation Name: Australian Safety and Efficacy Register of New Interventional Procedures-Surgical
Contact Address: ASERNIP-S 24 King William Street, Kent Town SA 5067 Australia Tel: +61 8 8219 0900
Contact Name: racs.asernip@surgeons.org
Contact Email: racs.asernip@surgeons.org
Copyright: <p>Australian Safety and Efficacy Register of New Interventional Procedures - Surgical</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.