Cerecyte (bioactive) coils for the treatment of intracranial aneurysms

Australian Safety and Efficacy Register of New Interventional Procedures - Surgical (ASERNIP-S)
Record ID 32011000725
English
Authors' recommendations: From the limited literature available (five small observational studies), Cerecyte coils appear to be safe with occlusion/recanalisation rates that are as good or better than bare platinum coils (the traditional standard) for treatment of ruptured and unruptured intracerebral aneurysms. The technology was approved several years ago in a number of countries and appears to be in at least limited use. Cost data were not available in order to determine the financial impact of switching to Cerecyte (or its competitors) from bare platinum coils. At least one multicentre RCT will report within the next year or two, thus adding to the evidence base for this technology.The Cerecyte coil is seeing limited use in several countries based on small observational studies that have shown it to be safe and at least as effective as bare platinum coils for the treatment of ruptured or unruptured intracranial aneurysms. A large RCT of Cerecyte coils is currently underway at 24 centres in six countries. As results from the observational studies do not unequivocally establish its benefits over bare platinum coils, decision makers may wish to defer an opinion until the RCT results are available. Based on this it is recommended that the technology be monitored for 12 months.
Details
Project Status: Completed
Year Published: 2010
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Australia
MeSH Terms
  • Angiography
  • Embolization, Therapeutic
  • Intracranial Aneurysm
  • Microsurgery
  • Platinum
Contact
Organisation Name: Australian Safety and Efficacy Register of New Interventional Procedures-Surgical
Contact Address: ASERNIP-S 24 King William Street, Kent Town SA 5067 Australia Tel: +61 8 8219 0900
Contact Name: racs.asernip@surgeons.org
Contact Email: racs.asernip@surgeons.org
Copyright: Australian Safety and Efficacy Register of New Interventional Procedures - Surgical (ASERNIP-S)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.