Temporary treatment cessation compared with continuation of tyrosine kinase inhibitors for adults with renal cancer: the STAR non-inferiority RCT
Collinson F, Royle KL, Swain J, Ralph C, Maraveyas A, Eisen T, Nathan P, Jones R, Meads D, Wah TM, Martin A, Bestall J, Kelly-Morland C, Linsley C, Oughton J, Chan K, Theodoulou E, Arias-Pinilla G, Kwan A, Daverede L, Handforth C, Trainor S, Salawu A, McCabe C, Goh V, Buckley D, Hewison J, Gregory W, Selby P, Brown J, Brown J
            Record ID 32011000720
            English
                        
                Original Title:
                A randomised, multi-stage phase II/III study of standard first-line therapy (sunitinib or pazopanib) comparing temporary cessation with allowing continuation, in the treatment of locally advanced and/or metastatic renal cancer (the STAR trial)
            
                                                                        
            Details
                        
                Project Status:
                Completed
            
                                    
                URL for project:
                https://www.journalslibrary.nihr.ac.uk/programmes/hta/099121/#/
            
                                                
                Year Published:
                2024
            
                                    
                URL for published report:
                https://www.journalslibrary.nihr.ac.uk/hta/JWTR4127
            
                                    
                Requestor:
                NIHR Health Technology Assessment programme
            
                                                
                English language abstract:
                An English language summary is available
            
                                    
                Publication Type:
                Full HTA
            
                                    
                Country:
                England, United Kingdom
            
                                                            
            
                        MeSH Terms
            - Withholding Treatment
 - Kidney Neoplasms
 - Sunitinib
 - Carcinoma, Renal Cell
 - Antineoplastic Agents
 - Tyrosine Kinase Inhibitors
 - Protein Kinase Inhibitors
 
Contact
                        
                Organisation Name:
                NIHR Health Technology Assessment programme
            
            
                        
                Contact Address:
                NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
            
                                    
                Contact Name:
                journals.library@nihr.ac.uk
            
                                    
                Contact Email:
                journals.library@nihr.ac.uk
            
                                
                This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.