Positron emission tomography/computerised tomography imaging in detecting and managing recurrent cervical cancer: systematic review of evidence, elicitation of subjective probabilities and economic modelling

Meads C, Auguste P, Davenport C, MaƂysiak S, Sundar S, Kowalska M, Zapalska A, Guest P, Thangaratinam S, Martin-Hirsch P, Borowiack E, Barton P, Roberts T, Khan K
Record ID 32011000651
English
Authors' objectives: For the proposed project our objectives are as follows: In women who had undergone treatment for cervical cancer, under routine surveillance or with suspicion of recurrence: To assess if the addition of PET-CT to existing scans (CT or MRI) improves the detection of recurrent cervical cancer. To evaluate if the use of PET-CT results in change in (re)staging i.e. extent of recurrence compared to CT or MRI. To assess the impact of performing PET-CT on the planned treatment after diagnosis of recurrence and during subsequent monitoring. To summarise the effectiveness of available treatment in women with recurrent cervical cancer. To estimate the impact of PET CT findings patient outcomes and the costs associated with its routine use in this patient group.
Authors' recommendations: Study found that the addition of PET-CT to standard practice is not cost-effective in the diagnosis of recurrent or persistent cervical cancer but that should more reliable information become available on accuracy, therapeutic impact and effectiveness, and the cost of PET-CT decrease, this conclusion may need revision.
Details
Project Status: Completed
Year Published: 2013
URL for published report: http://www.hta.ac.uk/2217
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Female
  • Neoplasm Recurrence, Local
  • Neoplasm Staging
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed
  • Uterine Cervical Neoplasms
Contact
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name: journals.library@nihr.ac.uk
Contact Email: journals.library@nihr.ac.uk
Copyright: 2013 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.