Authors' recommendations: The use of AFV techniques, such as Velscope®, and autofluorescence spectroscopy have shown variable results in the detection of oral cancer. Furthermore, appropriateness of screening with devices that use spectroscopy has not been indicated in the literature reviewed. However, spectroscopy devices may serve as useful diagnostic adjuncts to help avoid unnecessary scalpel biopsy among patients with benign lesions, or providing better guidance for biopsy or surgery, when indicated. Conversely, the included study of Velscope indicated that considerable morbidity could result from false positives (through unnecessary invasive procedures) in a general population not at high risk of oral cancer, and many cancers could have delayed diagnosis as a result of cases missed by Velscope®These devices may serve as useful diagnostic adjuncts to help avoid unnecessary scalpel biopsy among patients with benign lesions, or providing better guidance for biopsy or surgery, when indicated. However, variable results were reported by studies included for assessment with the potential for increased morbidity from false positives. The levels of evidence assessed were low, and the use of Velscope to screen for oral cancer cannot be supported on the basis of the included diagnostic evidence. Therefore no further assessment of this technology is warranted.

Project Status: Completed

Year Published: 2010

URL for published report: Not Available

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: Australia

Organisation Name: Adelaide Health Technology Assessment

Contact Address: School of Public Health, Mail Drop 545, University of Adelaide, Adelaide SA 5005, AUSTRALIA, Tel: +61 8 8313 4617

Contact Name: ahta@adelaide.edu.au

Contact Email: ahta@adelaide.edu.au

Copyright: Adelaide Health Technology Assessment (AHTA)