Screening for bilirubin encephalopathy
Ip S, Chung M, Trikalinos T, DeVine D, Lau J
Record ID 32011000571
English
Authors' objectives:
To systematically review evidence for the effectiveness of strategies to prevent chronic bilirubin encephalopathy. This is an update of our previous evidence report.
Authors' recommendations:
A study that directly evaluates the effectiveness of different strategies to reduce the incidence of kernicterus is not feasible given the rare occurrence of kernicterus. For practical consideration, studies on the effectiveness of different strategies to reduce the incidence of bilirubin encephalopathy could only rely on a surrogate outcome like serum bilirubin level. Based on retrospective analyses among infants who had both early and late TSB measurements available, the combination of risk factors and early TSB measurement has better diagnostic ability to predict clinically significant hyperbilirubinemia compared to risk factors alone.
Details
Project Status:
Completed
URL for project:
http://www.ncbi.nlm.nih.gov/books/NBK34036/
Year Published:
2009
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Bilirubin
- Hyperbilirubinemia, Neonatal
- Mass Screening
Contact
Organisation Name:
Agency for Healthcare Research and Quality
Contact Address:
Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA. Tel: +1 301 427 1610; Fax: +1 301 427 1639;
Contact Name:
martin.erlichman@ahrq.hhs.gov
Contact Email:
martin.erlichman@ahrq.hhs.gov
Copyright:
Agency for Healthcare Research and Quality (AHRQ)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.