[Efficacy of oral/buccal insulin in the treatment of diabetes mellitus]

Herrador-Ortiz Z, Llanos-Mendez A
Record ID 32011000517
Authors' recommendations: Oral/buccal insulin gives similar or better results than injected insulin. The new treatment produced a greater and early reduction in post-prandial blood glucose compared to standard treatment, as well as a faster and shorter maximum insulin concentration. There are currently no long term clinical trials that demonstrate the safety and effectiveness of oral/buccal insulin. Studies of longer follow-up periods are required to evaluate long-term side effects. No cost-effectiveness publication has been identified. An important observation is that oral/buccal formulations require more total insulin per dose compared to injected insulin. This data suggests that there may be an increase in costs associated with insulin therapy.
Project Status: Completed
Year Published: 2010
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Spain
MeSH Terms
  • Administration, Buccal
  • Administration, Oral
  • Hypoglycemic Agents
  • Insulin
Organisation Name: Andalusian Health Technology Assessment Area
Contact Address: Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. InnovaciĆ³n, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
Contact Name: aetsa.csalud@juntadeandalucia.es
Contact Email: aetsa.csalud@juntadeandalucia.es
Copyright: Andalusian Agency for Health Technology Assessment (AETSA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.