Authors' objectives:

To assess, in light of the existing scientific (medical) evidence, the relative contribution of radiotherapy to clinical management of lung cancer patients

Authors' recommendations: Radiotherapy is a useful therapeutic technique for pulmonary malignancy treatment (not only palliative), with a significant reduction of the size of the lesions, increase in Survival Time, Time to Progression, Disease Free Survival Time and decrease of Relapses. There are powerful indications based on MA that the most useful mode of administering RTP would be the concurrent chemo-RTP. In some Studies this option increases the number of serious toxicities, even death. But in other studies is not the same. This means that we should administer concurrent chemo-RTP in a way that we could get this benefit surplus, avoiding the fatal/serious complications. We recommend strongly to undertake more RCT studies to determine in a secure way the manner of administering concurrent chemo-RTP without incremental of toxicities. Also we recommend strongly to carry out more MAs to confirm with a greater number of patients the results we have obtained in this report.

Project Status: Completed

URL for project: http://www.isciii.es/htdocs/publicaciones/documentos/62_Radioterapia_cancer_pulmon.pdf

Year Published: 2010

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: Spain

Organisation Name: Agencia de Evaluacion de Tecnologias Sanitarias

Contact Address: Instituto de Salud "Carlos III", Calle Sinesio Delgado 6, Pabellon 4, 28029 Madrid, Spain. Tel: +34 9 1 822 2005; Fax: +34 9 1 387 7841;

Contact Name: Luis M. Sánchez Gómez

Contact Email: luism.sanchez@isciii.es

Copyright: Agencia de Evaluacion de Tecnologias Sanitarias (AETS)