[Trabectedin (Yondelis) in the treatment of soft tissue sarcomas]

Comite d'Avaluacio de Medicaments d'Utilitzacio Hospitalaria (CAMUH)
Record ID 32011000243
Catalan, English
Authors' objectives:

To assess the efficacy, safety and efficiency of trabectedin in the treatment of STS in adult patients and to define indication criteria in the public setting of the Catalan Health Service-CatSalut.

Authors' recommendations: There are no studies that compare trabectedin to other treatment alternatives, including placebo or support treatment. Most available data on trabectedin pertain to patients with leiomyosarcoma or liposarcoma, in whom it seems the main effect would result from the induction or maintenance of disease stabilization. The scientific evidence available at the time of trabectedin approval is very limited and for this reason trabectedin is considered a restricted-use drug. Clinical criteria for treatment indications are defined in the public setting of the CatSalut.
Details
Project Status: Completed
URL for project: http://www.gencat.cat/salut/depsan/units/aatrm/html/en/dir393/doc13828.html
Year Published: 2010
URL for published report: http://www.gencat.cat/salut/depsan/units/aatrm/pdf/trabectedina_sarcoma_teixitstous_aiaqs_2010ca.pdf
URL for additional information: http://www.gencat.cat/salut/depsan/units/aatrm/pdf/trabectedina_recomanacions_aiaqs2010ca.pdf
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Spain
MeSH Terms
  • Antineoplastic Agents, Alkylating
  • Sarcoma
  • Soft Tissue Neoplasms
  • Tetrahydroisoquinolines
Contact
Organisation Name: Agencia de Qualitat i Avaluacio Sanitries de Catalunya
Contact Address: Antoni Parada, CAHTA, Roc Boronat, 81-95 (2nd floor), 08005 Barcelona, Spain, Tel. +34 935 513 928, Fax: +34 935 517 510
Contact Name: direccio@aatrm.catsalut.net / aparada@aatrm.catsalut.net
Contact Email: direccio@aatrm.catsalut.net / aparada@aatrm.catsalut.net
Copyright: Catalan Agency for Health Information, Assessment and Quality (CAHIAQ)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.