[Alglucosidase alpha (Myozyme) for treatment of patients with late-onset Pompe disease]
Comite d'Avaluacio de Medicaments d'Utilitzacio Hospitalaria (CAMUH)
Record ID 32011000221
Catalan
Authors' objectives:
To analyse the available scientific evidence for efficacy, safety and efficiency of alglucosidase alpha compared with any other treatment, including placebo, in patients with late-onset Pompe disease.
Authors' recommendations:
Alglucosidase alpha is generally well tolerated and improves walking distance and stabilises pulmonary function in patients with late-onset Pompe disease after 18 months of treatment. The effect of alpha glucosidase antibodies on the drug pharmacodynamics has not been established.
Details
Project Status:
Completed
Year Published:
2011
URL for published report:
http://www.gencat.cat/salut/depsan/units/aatrm/pdf/alglucosidasa_alfa_pompe_aiaqs2011ca.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Spain
MeSH Terms
- alpha-Glucosidases
- Spain
Contact
Organisation Name:
Agencia de Qualitat i Avaluacio Sanitries de Catalunya
Contact Address:
Antoni Parada, CAHTA, Roc Boronat, 81-95 (2nd floor), 08005 Barcelona, Spain, Tel. +34 935 513 928, Fax: +34 935 517 510
Contact Name:
direccio@aatrm.catsalut.net / aparada@aatrm.catsalut.net
Contact Email:
direccio@aatrm.catsalut.net / aparada@aatrm.catsalut.net
Copyright:
Catalan Agency for Health Information, Assessment and Quality (CAHIAQ)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.