Implantable contraceptives (subdermal implants and hormonally impregnated intrauterine systems) versus other forms of reversible contraceptives: two systematic reviews to assess relative effectiveness, acceptability, tolerability and cost-effectiveness

French R S, Procter T, Cowan F M, Hughes D, Mansour D J A, Robinson A, Morris S, Guillebaud J
Record ID 32000000833
Authors' objectives:

The aims of this study are: - To assess the contraceptive efficacy, tolerability and acceptability of subdermal implants and IUSs in comparison with other reversible contraceptive methods. - To use these data to determine the relative cost-effectiveness.

Authors' recomendations: There was insufficient evidence from the comparative studies included in these systematic reviews to suggest that one type of subdermal implant was any more or less effective in preventing pregnancy than another, that implants were any more or less effective than the other methods with which they were compared, or that the LNG-20 IUS was any more or less effective than IUDs > 250 mm3. LNG-20 IUS users were significantly less likely to experience either intrauterine or extrauterine pregnancies than were IUD <3 users. Women using the LNG-20 IUS were more likely to experience amenorrhoea, and this event was a notable reason for discontinuation of IUSs.
Authors' methods: Systematic review
Project Status: Completed
URL for project:
Year Published: 2000
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Cost-Benefit Analysis
  • Injections, Subcutaneous
  • Patient Satisfaction
  • Pregnancy
  • Prospective Studies
  • Technology Assessment, Biomedical
  • Treatment Outcome
  • Contraceptive Agents, Female
  • Drug Implants
  • Intrauterine Devices, Medicated
  • Levonorgestrel
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name:
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Copyright: 2009 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.