Renal sympathetic denervation for the treatment of resistant hypertension

Mundy L, Hiller JE
Record ID 32010001660
English
Authors' recommendations: Based on the low level of available evidence it would appear that renal denervation may be a viable option for the treatment of resistant hypertension. Blood pressure was significantly lower after renal denervation than that measured at baseline, however it is unclear whether this decrease is considered clinically significant. Final 12-month follow-up data were only reported for a small portion of the enrolled patients (22%) and in addition, six of the 45 patients were considered non-responders with non-significant reductions in blood pressure. A well conducted randomised controlled trial is needed to adequately investigate whether renal denervation is capable of producing a sustained lowering of blood pressure in hypertensive patients resistant to medication.Renal denervation appears to be an innovative and promising technique for the treatment of resistant hypertension. HealthPACT have recommended that further information from clinical trials be assessed in 24-months time.
Details
Project Status: Completed
Year Published: 2010
URL for published report: Not Available
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Australia
MeSH Terms
  • Hypertension
  • Catheter Ablation
  • Sympathectomy
  • Blood Pressure
  • Denervation
Contact
Organisation Name: Adelaide Health Technology Assessment
Contact Address: School of Public Health, Mail Drop 545, University of Adelaide, Adelaide SA 5005, AUSTRALIA, Tel: +61 8 8313 4617
Contact Name: ahta@adelaide.edu.au
Contact Email: ahta@adelaide.edu.au
Copyright: <p>Adelaide Health Technology Assessment (AHTA) on behalf of NICS</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.