Outcomes of genetic testing in adults with a history of venous thromboembolism
Segal JB, Brotman DJ, Emadi A, Necochea AJ, Samal L, Wilson LM, Crim MT, Bass EB
Record ID 32010001606
English
Authors' recommendations:
There is no direct evidence that testing for these mutations leads to improved clinical outcomes in adults with a history of VTE or their adult family members. The literature supports the conclusion that while these assays have high analytic validity, the test results have variable clinical validity for predicting VTE in these populations and have only weak clinical utility.
Details
Project Status:
Completed
URL for project:
http://www.ahrq.gov/downloads/pub/evidence/pdf/factorvleiden/fvl.pdf
Year Published:
2009
URL for published report:
http://www.ahrq.gov/clinic/tp/fvltp.htm
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Adult
- Mutation
- Randomized Controlled Trials as Topic
- Treatment Outcome
- Factor V
- Genetic Markers
- Prothrombin
- Venous Thromboembolism
Contact
Organisation Name:
Agency for Healthcare Research and Quality
Contact Address:
Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA. Tel: +1 301 427 1610; Fax: +1 301 427 1639;
Contact Name:
martin.erlichman@ahrq.hhs.gov
Contact Email:
martin.erlichman@ahrq.hhs.gov
Copyright:
Agency for Healthcare Research and Quality (AHRQ)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.