[Economic evaluation of monitoring systems of ketones in blood for the diagnosis and prevention of ketoacidosis]

Espin Balbino J, Garcia Mochon L, Epstein D
Record ID 32010001487
English, Spanish
Authors' recomendations: With a probability of severe event of 24% for 6 months, a RO of 0.61 and a test execution of 0.28, the incremental cost per severe event avoided in the use of capillary ketone per is € 1.273. Drawing any conclusion about the cost-effectiveness is diffi cult since there are no data to estimate the quality of life of a patient type 1 with ketosis in Spain. If we consider that the health service might be willing to pay € 30,000 per additional healthylife year, and that a serious adverse event results in up to one week with very low quality of life, then the health service might be willing to pay up to € 577 for each event avoided. Under these assumptions, blood ketone tests would not be cost-effective for the base case. Blood ketone testing might be cost-effective under alternative scenarios, for instance in patients with a higher expected prevalence of severe events, or if a blood test strip cost less than € 1.5. These results indicate that determining the presence of ketonic bodies by capillary blood ketone testing is not cost-effective with patients having a good control of glucose and a low risk of ketosis. However, costeffectiveness may be greater in patients at a high risk or if the blood strip cost was lower. Moreover, the results are very sensitive to the frequency of ketonic body determination and the odds ratio of a severe event with capillary blood ketone testing versus urine testing.
Project Status: Completed
Year Published: 2010
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Spain
MeSH Terms
  • Blood Glucose Self-Monitoring
  • Cost-Benefit Analysis
  • Ketones
  • Monitoring, Physiologic
  • Diabetic Ketoacidosis
Organisation Name: Andalusian Health Technology Assessment Area
Contact Address: Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. Innovación, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
Contact Name: aetsa.csalud@juntadeandalucia.es
Contact Email: aetsa.csalud@juntadeandalucia.es
Copyright: Andalusian Agency for Health Technology Assessment (AETSA)
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