[Radiofrequency ablation of breast tumours]

Llanos Mendez A, Villegas Portero R
Record ID 32010001467
English, Spanish
Authors' recommendations: Research into the efficacy of radiofrequency ablation (RFA) for the treatment of localised breast tumours is in its initial stages, in which the main aim is to determine the safety of the technique and obtain preliminary data on its efficacy.For this reason, only phase I and II clinical trials have been sourced.In general, the studies used mid-point results, observing complete loss of cell viability in the ablation area in most patients.Only one study had produced survival data, though not contrasted with the control group.No serious adverse effects were recorded.Certain circumstances, such as the limited effectiveness of ultrasound in assessing tumour size, or in detecting the presence of distal foci, as well as variations in the density and size of the breast tissue, may affect the efficacy of this technique.More research is needed to determine if the use of RFA as a sole local treatment for primary breast cancer would result in local recurrence and survival rates comparable to cases that have undergone conservative therapies, which are currently standard practice in most cases of small breast tumours.No economic data are available to assess the potential impact on the healthcare system of introducing the technique.
Details
Project Status: Completed
Year Published: 2007
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Spain
MeSH Terms
  • Breast Neoplasms
Contact
Organisation Name: Andalusian Health Technology Assessment Area
Contact Address: Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. InnovaciĆ³n, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
Contact Name: aetsa.csalud@juntadeandalucia.es
Contact Email: aetsa.csalud@juntadeandalucia.es
Copyright: Andalusian Agency for Health Technology Assessment (AETSA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.